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Biospecimen Procurement
BioChain has been collecting biospecimens for over 20 years. We have extensive connections with various vendors and facilities to procure IRB approved and consented samples. Our procurement and processing procedure is stream-lined to offer systematic and quality samples to support unique biospecimen requirements.
Example of completed Projects for Pharmaceutics and Diagnostics:
- 400 FFPE lung cancer samples, 200 matched serum samples collected, perform FFPE tissue and circulating DNA isolation, perform real time PCR with Roche LC480
- Collect FFPE+ Blood separated into plasma + rest of blood from 162 donors from 10 different tumor types
- 4 types of Matched Paired frozen tumor tissue, 25-30 donors from each type of tumor
- BRCA1 and BRCA2 NGS Characterization for 200 breast donor Frozen samples
Service Overview
BioChain provides the pharmaceutical and biotech industry with clinical sample collection and analysis services. Some case studies are described below.
Sample Collection:
- Cancer patients’ body fluid and tumor samples according to various customers’ specifications
- Various normal and diseased tissues from autopsy
- Collection of other types of samples may be available upon request
Sample Preparation:
- DNA/RNA/Protein Isolation
- Tissue Sections and Tissue Arrays
- Making sections on printed slides from FFPE blocks either procured by BioChain or provided by customers
Sample Analysis:
- PCR and NGS analysis for DNA and RNA
- Western Analysis of Protein lysate
- IHC and ISH test for tissue sections and tissue arrays
Feature & Benefits
- The samples are IRB-approved and retrieved from consented donors
- Meticulously selected and identified by our board licensed pathologist
- Can be used to perform histology tests and biomarker analysis, for the development of diagnostics or therapeutics
- Ability to view our digitally scanned H&E image slides and pathology datasheet information
Example Case Study
Inquiry: A Principle Investigator “PI” needed to collect 400 NSCLC FFPE blocks and 2 ml plasma from each donor and could not find a cost effective supplier to provide the samples.
Solution: BioChain was able to collect all of the samples and provide the tissue section and isolated the DNA from the samples.
Need biospecimens from multiple donors?
Reach out to us to customize your project! We offer custom sample procurement, custom frozen and FFPE tissue sectioning and more!
Other Custom Services
OEM Manufacturing
BioChain has been ISO certified for more than 10 yrs (ISO9001:2015 and ISO 13485:2016) and has established standard state-of-the-art SOPs and OEM processing.
Custom Extraction & Purification
BioChain has developed proprietary reagents for the extraction of biomolecules from a wide variety of sample types.
Histology Services
Our custom immunohistochemistry services assist customers with antibody validation and protein localization analysis.
